Benzenemethanamine, 2-(2,2,2-trifluoroethoxy)- - Names and Identifiers
Name | [2-(2,2,2-trifluoroethoxy)phenyl]methanamine
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Synonyms | 2-(2,2,2-Trifluoro-ethoxy)-benzylamine 2-(2,2,2-Trifluoroethoxy)-benzyl aMine HCl [2-(2,2,2-trifluoroethoxy)phenyl]methanamine BenzeneMethanaMine, 2-(2,2,2-trifluoroethoxy)- 1-[2-(2,2,2-trifluoroethoxy)phenyl]methanamine Benzenemethanamine, 2-(2,2,2-trifluoroethoxy)-
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CAS | 342816-26-6
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Benzenemethanamine, 2-(2,2,2-trifluoroethoxy)- - Physico-chemical Properties
Benzenemethanamine, 2-(2,2,2-trifluoroethoxy)- - Introduction
[2-(2,2,2-trifluoroethoxy)phenyl]methanamine is a chemical compound with the formula C9H10F3NO2 · HCl. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White solid
-solubility: low solubility in water, soluble in organic solvents such as chloroform, ether
-Melting point: 165-168°C
-Molecular mass: 267.64g/mol
Use:
-In chemical synthesis, it can be used as an important intermediate and catalyst
-can be used in organic synthesis reaction reduction, N-arylation
Preparation Method:
The synthesis of [2-(2,2,2-trifluoroethoxy)phenyl]methanamine can be completed by the following steps:
1. benzyl chloride reacts with 2,2, 2-trifluoroethanol to generate the corresponding 2-(2,2, 2-trifluoroethoxy) benzyl chloride.
2.2-(2,2, 2-trifluoroethoxy) benzyl chloride reacts with benzylamine to generate 2-(2,2, 2-trifluoroethoxy)-benzylamine.
3.2-(2,2,2-trifluoroethoxy)-benzylamine is treated with hydrochloric acid to give [2-(2,2,2-trifluoroethoxy)phenyl]methanamine.
Safety Information:
-In handling, use and storage, appropriate safety measures need to be taken to avoid direct contact with skin and eyes, and to prevent inhalation or ingestion.
-Store this compound in a dry, well-ventilated place, away from ignition and oxides.
-When handling this compound, please follow local safety procedures and laboratory safety guidelines.
Last Update:2024-04-10 22:29:15